Ospreys wing Eli Walker has been ruled out of Saturday's Test against South Africa due to injury.
The 21-year-old, who was due to make his debut against the Springboks at the Millennium Stadium, suffered a hamstring injury in training Thursday morning.
He will be replaced on the wing by Liam Williams (Scarlets).
Williams' place amongst the replacements will be taken by Ashley Beck (Ospreys).
Wales - revised: 15 Leigh Halfpenny, 14 George North, 13 Jonathan Davies, 12 Scott Williams, 11 Liam Williams, 12 Rhys Priestland, 9 Mike Phillips, 8 Toby Faletau, 7 Sam Warburton (captain), 6 Dan Lydiate, 5 Alun Wyn Jones, 4 Bradley Davies, 3 Adam Jones, 2 Richard Hibbard, 1 Gethin Jenkins.
Replacements: 16 Ken Owens, 17 Paul James, 18 Scott Andrews, 19 Luke Charteris, 20 Justin Tipuric 21 Lloyd Williams, 22 James Hook, 23 Ashley Beck.
Date: Saturday, November 9
Venue: Millennium Stadium, Cardiff
Kick-off: 17.30 (17.30 GMT; 19.30 SA time)
Referee: Alain Rolland (Ireland)
Assistant referees: George Clancy (Ireland), Marius Mitrea (Italy)
TMO: Eric Gauzins (France)