Prop Thomas Domingo and No.8 Louis Picamoles were recalled to the 30-strong French preliminary squad for Saturday's Test match against South Africa at the Stade de France.
They take over from lock Yoann Maestri, who is suspended after being sent off against Tonga at Le Havre on Saturday, and flank Fulgence Ouedraogo, who injured a shoulder in the same match.
The rest of the squad is unchanged, as coach Philippe Saint-Andre looks for another win following the 26-19 defeat at the hands of New Zealand and the 38-18 victory over the Tongans.
Picamoles returns to the fold after missing several games due to a troublesome hip injury, having won 38 caps previously.
Domingo had been sidelined with a knee injury sustained playing for his club side Clermont in October.
Forwards: Vincent Debaty, Thomas Domingo, Yannick Forestier, Benjamin Kayser, Dimitri Szarzewski, Nicolas Mas, Rabah Slimani, Alexandre Flanquart, Pascal Pape, Sébastien Vahaamahina, Thierry Dusautoir (captain), Wenceslas Lauret, Bernard Leroux, Yannick Nyanga, Antonie Claassen, Damien Chouly, Louis Picamoles.
Backs: Jean-Marc Doussain, Morgan Parra, Jonathan Pelissie, Frédéric Michalak, Rémi Tales, Mathieu Bastareaud, Gaël Fickou, Wesley Fofana, Florian Fritz, Sofiane Guitoune, Maxime Medard, Yoann Huget, Brice Dulin.