Captain Sergio Parisse returns for winless Italy's starting side as the Azzurri look to cap a disappointing Six Nations campaign with a win against title hopefuls England in Rome on Saturday.
Italy coach Jacques Brunel made three changes to the side that started against Ireland last week where the Azzurri suffered a 47-7 defeat.
Parisse returns at No.8 in place of Paul Derbyshire, while in the front row Lorenzo Cittadini replaces injured prop Martin Castrogiovanni and Matias Aguero comes in for Alberto De Marchi, who drops to the bench.
Castrogiovanni failed to recover from the injury he suffered to his ribs against Ireland in Dublin.
Italy: 15 Luke McLean, 14 Angelo Esposito, 13 Michele Campagnaro, 12 Gonzalo Garcia, 11 Leonardo Sarto, 10 Luciano Orquera, 9 Tito Tebaldi, 8 Sergio Parisse (captain), 7 Robert Barbieri, 6 Joshua Furno, 5 Marco Bortolami, 4 Quintin Geldenhuys, 3 Lorenzo Cittadini, 2 Leonardo Ghiraldini, 1 Matias Aguero.
Replacements: 16 Davide Giazzon, 17 Michele Rizzo, 18 Alberto De Marchi, 19 George Biagi, 20 Paul Derbyshire, 21 Edoardo Gori, 22 Tommaso Allan, 23 Andrea Masi
Date: Saturday, March 15
Venue: Stadio Olimpico, Rome
Kick-off: 13.30 (12.30 UK time, 12.30 GMT)
Referee: Pascal Gauzère (France)
Assistant referees: Nigel Owens (Wales), Leighton Hodges (Wales)
TMO: Simon McDowell (Ireland)