Victor Matfield will captain the Bulls for the first time in two years when they host the Sharks in Pretoria on Saturday.
Matfield takes over the captaincy from fellow Springbok Flip van der Merwe, who pulled out of the Round Six Super Rugby encounter with a hamstring injury on Thursday.
Paul Willemse comes off the bench to partner Matfield in the second row.
Grant Hattingh, who was due to play for the Blue Bulls in the Vodacom Cup clash against the Golden Lions on Saturday, has been promoted to the bench for the Super Rugby team.
Bulls - revised: 15 Jurgen Visser, 14 Sampie Mastriet, 13 JJ Engelbrecht, 12 Jan Serfontein, 11 Bjorn Basson, 10 Jacques-Louis Potgieter, 9 Francois Hougaard, 8 Dewald Potgieter, 7 Jacques du Plessis, 6 Deon Stegmann, 5 Victor Matfield (captain), 4 Paul Willemse, 3 Werner Kruger, 2 Callie Visagie, 1 Dean Greyling.
Replacements: 16 Bongi Mbonambi, 17 Morné Mellett, 18 Marcel van der Merwe, 19 Grant Hattingh, 20 Jono Ross, 21 Piet van Zyl, 22 Handré Pollard, 23 Ulrich Beyers.
Date: Saturday, March 22
Venue: Loftus Versfeld, Pretoria
Kick-off: 19.10 (17.10 GMT)
Referee: Mike Fraser (New Zealand)
Assistant referees: Craig Joubert (South Africa), Jaco van Heerden (South Africa)
TMO: Deon van Blommenstein (South Africa)