France and Toulon utility back Frederic Michalak faces at least three weeks on the sidelines with a dislocated shoulder.
Wales are set to be the dominant nation when coach Warren Gatland announces his squad next month for the B&I Lions tour.
The French team has soul and spirit despite a disastrous Six Nations campaign that saw them land the wooden spoon for the first time since 1999.
England coach Stuart Lancaster insisted his youthful side would learn from a record-breaking 3-30 loss to Wales.
Italian coach Jacques Brunel insisted his side have plenty to do if they are to become a true force to be reckoned with.
Scotland must progress from being a side that gets close to beating top teams into becoming actual winners, their interim coach Scott Johnson insisted.
Rob Howley forecast several Wales players would be returning to Australia with the British and Irish Lions after they retained their Six Nations title.
France landed the dreaded wooden spoon despite beating Scotland 23-16 at the Stade de France in their final Six Nations match.
Wales thrashed England by a record-breaking 30-3 at the Millennium Stadium to retain the Six Nations title and deny the visitors a Grand Slam.
Italy beat Ireland for the first time in the Six Nations as the Azzurri triumphed 22-15 in the Stadio Olimpico on Saturday.